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Functional association between promoter structure and transcript alternative splicing

It has been assumed that constitutive and regulated splicing of RNA polymerase II transcripts depends exclusively on signals present in the RNA molecule. Here we show that changes in promoter structure strongly affect splice site selection. We investigated the splicing of the ED I exon, which encode...

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Détails bibliographiques
Auteurs principaux: Cramer, Paula, Pesce, C. Gustavo, Baralle, Francisco E., Kornblihtt, Alberto R.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences of the USA 1997
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC23504/
https://ncbi.nlm.nih.gov/pubmed/9326631
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