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Role of Intrinsic Flexibility in Signal Transduction Mediated by the Cell Cycle Regulator, p27(Kip1)
p27(Kip1) (p27), which controls eukaryotic cell division through interactions with cyclin-dependent kinases (Cdks), integrates and transduces pro-mitogenic signals from various non-receptor tyrosine kinases (NRTKs) by orchestrating its own phosphorylation, ubiquitination and degradation. Intrinsic f...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2350195/ https://ncbi.nlm.nih.gov/pubmed/18177895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.016 |
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