Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2

The BCL-2 family of proteins is composed of both pro- and antiapoptotic regulators, although its most critical biochemical functions remain uncertain. The structural similarity between the BCL-X(L) monomer and several ion-pore-forming bacterial toxins has prompted electrophysiologic studies. Both BA...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Schlesinger, Paul H., Gross, Atan, Yin, Xiao-Ming, Yamamoto, Kazuhito, Saito, Mitsuyoshi, Waksman, Gabriel, Korsmeyer, Stanley J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9326614/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.21.11357
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