Identification of Novel Isoforms of the BH3 Domain Protein Bim Which Directly Activate Bax To Trigger Apoptosis

Bim (Bcl-2-interacting mediator of cell death) is a member of the BH3 domain-only subgroup of Bcl-2 family members, for which three splice variants have been described. Bim is expressed in many healthy cell types, where it is maintained in an inactive conformation through binding to the microtubule-...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Marani, Michela, Tenev, Tencho, Hancock, David, Downward, Julian, Lemoine, Nicholas R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133811/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997495/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.11.3577-3589.2002
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