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Identification of Novel Isoforms of the BH3 Domain Protein Bim Which Directly Activate Bax To Trigger Apoptosis

Bim (Bcl-2-interacting mediator of cell death) is a member of the BH3 domain-only subgroup of Bcl-2 family members, for which three splice variants have been described. Bim is expressed in many healthy cell types, where it is maintained in an inactive conformation through binding to the microtubule-...

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Bibliografske podrobnosti
Main Authors: Marani, Michela, Tenev, Tencho, Hancock, David, Downward, Julian, Lemoine, Nicholas R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC133811/
https://ncbi.nlm.nih.gov/pubmed/11997495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3577-3589.2002
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