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Identification of Novel Isoforms of the BH3 Domain Protein Bim Which Directly Activate Bax To Trigger Apoptosis

Bim (Bcl-2-interacting mediator of cell death) is a member of the BH3 domain-only subgroup of Bcl-2 family members, for which three splice variants have been described. Bim is expressed in many healthy cell types, where it is maintained in an inactive conformation through binding to the microtubule-...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Marani, Michela, Tenev, Tencho, Hancock, David, Downward, Julian, Lemoine, Nicholas R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133811/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997495/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.11.3577-3589.2002
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