Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2

The BCL-2 family of proteins is composed of both pro- and antiapoptotic regulators, although its most critical biochemical functions remain uncertain. The structural similarity between the BCL-X(L) monomer and several ion-pore-forming bacterial toxins has prompted electrophysiologic studies. Both BA...

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Bibliografiske detaljer
Main Authors: Schlesinger, Paul H., Gross, Atan, Yin, Xiao-Ming, Yamamoto, Kazuhito, Saito, Mitsuyoshi, Waksman, Gabriel, Korsmeyer, Stanley J.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC23466/
https://ncbi.nlm.nih.gov/pubmed/9326614
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