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Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA

Activation of the cystic fibrosis transmembrane conductance regulator (CFTR) channel by protein kinase A (PKA) is enhanced by protein kinase C (PKC). However, the mechanism of modulation is not known and it remains uncertain whether PKC acts directly on CFTR or through phosphorylation of an ancillar...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chappe, V, Hinkson, D A, Zhu, T, Chang, X-B, Riordan, J R, Hanrahan, J W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342791/
https://ncbi.nlm.nih.gov/pubmed/12588899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.035790
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