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Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA
Activation of the cystic fibrosis transmembrane conductance regulator (CFTR) channel by protein kinase A (PKA) is enhanced by protein kinase C (PKC). However, the mechanism of modulation is not known and it remains uncertain whether PKC acts directly on CFTR or through phosphorylation of an ancillar...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2342791/ https://ncbi.nlm.nih.gov/pubmed/12588899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.035790 |
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