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RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K(+) channels
G protein-gated inward rectifier K(+) (GIRK) channels mediate hyperpolarizing postsynaptic potentials in the nervous system and in the heart during activation of Gα(i/o)-coupled receptors. In neurons and cardiac atrial cells the time course for receptor-mediated GIRK current deactivation is 20–40 ti...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences of the USA
1997
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23385/ https://ncbi.nlm.nih.gov/pubmed/9294233 |
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