RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K(+) channels

G protein-gated inward rectifier K(+) (GIRK) channels mediate hyperpolarizing postsynaptic potentials in the nervous system and in the heart during activation of Gα(i/o)-coupled receptors. In neurons and cardiac atrial cells the time course for receptor-mediated GIRK current deactivation is 20–40 ti...

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Hlavní autoři: Doupnik, Craig A., Davidson, Norman, Lester, Henry A., Kofuji, Paulo
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1997
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC23385/
https://ncbi.nlm.nih.gov/pubmed/9294233
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