Crystallization and preliminary crystallographic analysis of hygromycin B phosphotransferase from Escherichia coli

Aminoglycoside antibiotics, such as hygromycin, kanamycin, neomycin, spectinomycin and streptomycin, inhibit protein synthesis by acting on bacterial and eukaryotic ribosomes. Hygromycin B phosphotransferase (Hph; EC 2.7.1.119) converts hygromycin B to 7′′-O-phosphohygromycin using a phosphate moiet...

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Detalhes bibliográficos
Main Authors: Iino, Daisuke, Takakura, Yasuaki, Kuroiwa, Mika, Kawakami, Ryouta, Sasaki, Yasuyuki, Hoshino, Takayuki, Ohsawa, Kanju, Nakamura, Akira, Yajima, Shunsuke
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
Assuntos:
Crystallization Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335168/
https://ncbi.nlm.nih.gov/pubmed/17671368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107032757
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