Expression of Hygromycin Phosphotransferase Alters Virulence of Histoplasma capsulatum

The Escherichia coli hygromycin phosphotransferase (hph) gene, which confers hygromycin resistance, is commonly used as a dominant selectable marker in genetically modified bacteria, fungi, plants, insects, and mammalian cells. Expression of the hph gene has rarely been reported to induce effects ot...

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Bibliographic Details
Main Authors: Smulian, A. George, Gibbons, Reta S., Demland, Jeffery A., Spaulding, Deborah T., Deepe, George S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168422/
https://ncbi.nlm.nih.gov/pubmed/17873086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00139-07
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