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Heating of proteins as a means of improving crystallization: a successful case study on a highly amyloidogenic triple mutant of human transthyretin

The use of high temperatures in the purification procedures of heat-stable proteins is a well established technique. Recently, rapid pre-heat treatment of protein samples prior to crystallization trials was described as a final polishing step to improve the diffraction properties of crystals [Pusey...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Karlsson, Anders, Sauer-Eriksson, A. Elisabeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335167/
https://ncbi.nlm.nih.gov/pubmed/17671371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107033957
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