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Design, synthesis and crystallization of a novel glucagon analog as a therapeutic agent
Glucagon and glucagon-like peptide 1 (GLP-1) are drugs or drug candidates for the treatment of metabolic diseases such as diabetes and obesity. The native hormones have pharmacological deficiencies such as short half-life and poor solubility. A novel glucagon receptor agonist named glucagon-Cex has...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
International Union of Crystallography
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2335127/ https://ncbi.nlm.nih.gov/pubmed/17620721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107028655 |
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