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Design, synthesis and crystallization of a novel glucagon analog as a therapeutic agent

Glucagon and glucagon-like peptide 1 (GLP-1) are drugs or drug candidates for the treatment of metabolic diseases such as diabetes and obesity. The native hormones have pharmacological deficiencies such as short half-life and poor solubility. A novel glucagon receptor agonist named glucagon-Cex has...

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Hlavní autoři: Li, Pengyun, Rogers, Tanya, Smiley, David, DiMarchi, Richard D., Zhang, Faming
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335127/
https://ncbi.nlm.nih.gov/pubmed/17620721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107028655
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