Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

The scrapie prion protein (PrP(Sc)) is the major, and possibly the only, component of the infectious prion; it is generated from the cellular isoform (PrP(C)) by a conformational change. N-terminal truncation of PrP(Sc) by limited proteolysis produces a protein of ≈142 residues designated PrP 27–30,...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	James, Thomas L., Liu, He, Ulyanov, Nikolai B., Farr-Jones, Shauna, Zhang, Hong, Donne, David G., Kaneko, Kiyotoshi, Groth, Darlene, Mehlhorn, Ingrid, Prusiner, Stanley B., Cohen, Fred E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294167/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.19.10086
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!