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A high-resolution structure of ligand-free human glutamate carboxypeptidase II

Human glutamate carboxypeptidase II (GCPII; EC 3.4.17.21) is an established marker for prostate-cancer diagnosis as well as a candidate therapeutic target for the treatment of diverse pathologies that involve glutamatergic transmission. Structural data on GCPII are thus valuable for the design and o...

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Autori principali: Barinka, Cyril, Starkova, Jana, Konvalinka, Jan, Lubkowski, Jacek
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330195/
https://ncbi.nlm.nih.gov/pubmed/17329803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910700379X
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