Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1

BACKGROUND: Development of therapies for patients with BRCA1 mutations has been hampered by lack of readily available in vitro and in vivo models. We recently showed that transplantation of transgenic mammary tumors as cell suspensions into naïve recipients generates reproducible tumors with remarka...

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Bibliografiske detaljer
Main Authors: Wright, Mollie H, Robles, Ana I, Herschkowitz, Jason I, Hollingshead, Melinda G, Anver, Miriam R, Perou, Charles M, Varticovski, Lyuba
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329667/
https://ncbi.nlm.nih.gov/pubmed/18394172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-29
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