Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors

The lack of markers to predict chemotherapy responses in patients poses a major handicap in cancer treatment. We searched for gene expression patterns that correlate with docetaxel or cisplatin response in a mouse model for breast cancer associated with BRCA1 deficiency. Array-based expression profi...

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Main Authors: Rottenberg, Sven, Vollebergh, Marieke A., de Hoon, Bas, de Ronde, Jorma, Schouten, Philip C., Kersbergen, Ariena, Zander, Serge A.L., Pajic, Marina, Jaspers, Janneke E., Jonkers, Martijn, Lodén, Martin, Sol, Wendy, van der Burg, Eline, Wesseling, Jelle, Gillet, Jean-Pierre, Gottesman, Michael M., Gribnau, Joost, Wessels, Lodewyk, Linn, Sabine C., Jonkers, Jos, Borst, Piet
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518318/
https://ncbi.nlm.nih.gov/pubmed/22396490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-4201
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