Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1

BACKGROUND: Development of therapies for patients with BRCA1 mutations has been hampered by lack of readily available in vitro and in vivo models. We recently showed that transplantation of transgenic mammary tumors as cell suspensions into naïve recipients generates reproducible tumors with remarka...

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Autori principali: Wright, Mollie H, Robles, Ana I, Herschkowitz, Jason I, Hollingshead, Melinda G, Anver, Miriam R, Perou, Charles M, Varticovski, Lyuba
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329667/
https://ncbi.nlm.nih.gov/pubmed/18394172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-29
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