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Histone H2A Monoubiquitination Represses Transcription by Inhibiting RNA Polymerase II Transcriptional Elongation
Solving the biological roles of covalent histone modifications, including monoubiqutination of histone H2A, and the molecular mechanisms by which these modifications regulate specific transcriptional programs, remains a central question for all eukaryotes. Here, we report that the N-CoR/HDAC1/3 comp...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327256/ https://ncbi.nlm.nih.gov/pubmed/18206970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.11.002 |
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