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Histone H2A Monoubiquitination Represses Transcription by Inhibiting RNA Polymerase II Transcriptional Elongation

Solving the biological roles of covalent histone modifications, including monoubiqutination of histone H2A, and the molecular mechanisms by which these modifications regulate specific transcriptional programs, remains a central question for all eukaryotes. Here, we report that the N-CoR/HDAC1/3 comp...

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Dettagli Bibliografici
Autori principali: Zhou, Wenlai, Zhu, Ping, Wang, Jianxun, Pascual, Gabriel, Ohgi, Kenneth A., Lozach, Jean, Glass, Christopher K., Rosenfeld, Michael G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327256/
https://ncbi.nlm.nih.gov/pubmed/18206970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.11.002
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