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Histone H2A Monoubiquitination Represses Transcription by Inhibiting RNA Polymerase II Transcriptional Elongation

Solving the biological roles of covalent histone modifications, including monoubiqutination of histone H2A, and the molecular mechanisms by which these modifications regulate specific transcriptional programs, remains a central question for all eukaryotes. Here, we report that the N-CoR/HDAC1/3 comp...

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Main Authors: Zhou, Wenlai, Zhu, Ping, Wang, Jianxun, Pascual, Gabriel, Ohgi, Kenneth A., Lozach, Jean, Glass, Christopher K., Rosenfeld, Michael G.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327256/
https://ncbi.nlm.nih.gov/pubmed/18206970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.11.002
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