Mucosal immunogenicity and adjuvant activity of the recombinant A subunit of the Escherichia coli heat-labile enterotoxin

The Escherichia coli heat-labile enterotoxin (LT) is an exceptionally effective mucosal immunogen and mucosal immunoadjuvant towards coadministered antigens. Although, in general, the molecular basis of these properties is poorly understood, both the toxic ADP-ribosylation activity of the LTA subuni...

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Main Authors: De Haan, L, Holtrop, M, Verweij, W R, Agsteribbe, E, Wilschut, J
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326879/
https://ncbi.nlm.nih.gov/pubmed/10457227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00817.x
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