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Role of GM1 binding in the mucosal immunogenicity and adjuvant activity of the Escherichia coli heat-labile enterotoxin and its B subunit.

Escherichia coli (E. coli) heat-labile toxin (LT) is a potent mucosal immunogen and immunoadjuvant towards co-administered antigens. LT is composed of one copy of the A subunit, which has ADP-ribosylation activity, and a homopentamer of B subunits, which has affinity for the toxin receptor, the gang...

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Detalhes bibliográficos
Main Authors: de Haan, L, Verweij, W R, Feil, I K, Holtrop, M, Hol, W G, Agsteribbe, E, Wilschut, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364263/
https://ncbi.nlm.nih.gov/pubmed/9767427
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