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Mucosal immunogenicity and adjuvant activity of the recombinant A subunit of the Escherichia coli heat-labile enterotoxin

The Escherichia coli heat-labile enterotoxin (LT) is an exceptionally effective mucosal immunogen and mucosal immunoadjuvant towards coadministered antigens. Although, in general, the molecular basis of these properties is poorly understood, both the toxic ADP-ribosylation activity of the LTA subuni...

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Détails bibliographiques
Auteurs principaux: De Haan, L, Holtrop, M, Verweij, W R, Agsteribbe, E, Wilschut, J
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326879/
https://ncbi.nlm.nih.gov/pubmed/10457227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00817.x
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