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A conformational switch in nuclear hormone receptors is involved in coupling hormone binding to corepressor release.

Nuclear hormone receptors are ligand-regulated transcription factors that modulate gene expression in response to small, hydrophobic hormones, such as retinoic acid and thyroid hormone. The thyroid hormone and retinoic acid receptors typically repress transcription in the absence of hormone and acti...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Lin, B C, Hong, S H, Krig, S, Yoh, S M, Privalsky, M L
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1997
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232463/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9315673/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.10.6131
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