A conformational switch in nuclear hormone receptors is involved in coupling hormone binding to corepressor release.

Nuclear hormone receptors are ligand-regulated transcription factors that modulate gene expression in response to small, hydrophobic hormones, such as retinoic acid and thyroid hormone. The thyroid hormone and retinoic acid receptors typically repress transcription in the absence of hormone and acti...

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Hlavní autoři: Lin, B C, Hong, S H, Krig, S, Yoh, S M, Privalsky, M L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC232463/
https://ncbi.nlm.nih.gov/pubmed/9315673
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