A conformational switch in nuclear hormone receptors is involved in coupling hormone binding to corepressor release.
Nuclear hormone receptors are ligand-regulated transcription factors that modulate gene expression in response to small, hydrophobic hormones, such as retinoic acid and thyroid hormone. The thyroid hormone and retinoic acid receptors typically repress transcription in the absence of hormone and acti...
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| Published in: | Mol Cell Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9315673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.10.6131 |
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