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Mapping Hsp47 binding site(s) using CNBr peptides derived from type I and type II collagen

As a crucial molecular chaperone in collagen biosynthesis, Hsp47 interacts with the nascent form as well as the mature triple-helical form of procollagen. The location(s) of Hsp47 binding sites on the collagen molecule are, as yet, unknown. We have examined the substrate specificity of Hsp47 in vitr...

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Auteurs principaux: Thomson, Christy A., Tenni, Ruggero, Ananthanarayanan, Vettai S.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323965/
https://ncbi.nlm.nih.gov/pubmed/12876328
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