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Mapping Hsp47 binding site(s) using CNBr peptides derived from type I and type II collagen
As a crucial molecular chaperone in collagen biosynthesis, Hsp47 interacts with the nascent form as well as the mature triple-helical form of procollagen. The location(s) of Hsp47 binding sites on the collagen molecule are, as yet, unknown. We have examined the substrate specificity of Hsp47 in vitr...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Cold Spring Harbor Laboratory Press
2003
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323965/ https://ncbi.nlm.nih.gov/pubmed/12876328 |
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