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Measuring the stability of partly folded proteins using TMAO

Standard methods for measuring free energy of protein unfolding by chemical denaturation require complete folding at low concentrations of denaturant so that a native baseline can be observed. Alternatively, proteins that are completely unfolded in the absence of denaturant can be folded by addition...

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Bibliografiske detaljer
Main Authors: Mello, Cecilia C., Barrick, Doug
Format: Artigo
Sprog:Inglês
Udgivet: Wiley-Blackwell 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323936/
https://ncbi.nlm.nih.gov/pubmed/12824497
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