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Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation.

The functionality of the p53-mediated pathway, activated in response to DNA damage, has been assessed in primary fibroblast cell cultures and Epstein-Barr virus-transformed lymphoblastoid cell lines derived from Nijmegen breakage syndrome (NBS) patients. This autosomal recessive disease is character...

詳細記述

保存先:
書誌詳細
出版年:Mol Cell Biol
主要な著者: Jongmans, W, Vuillaume, M, Chrzanowska, K, Smeets, D, Sperling, K, Hall, J
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232352/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9271379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.9.5016
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