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Monocytes prevent apoptosis of iPSCs and promote differentiation of kidney organoids

Abstract Background Induced pluripotent stem cells (iPSCs)-derived kidney organoids are a promising model for studying disease mechanisms and renal development. Despite several protocols having been developed, further improvements are needed to overcome existing limitations and enable a wider applic...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Ekaterina Pecksen, Sergey Tkachuk, Cristoph Schröder, Marc Vives Enrich, Anindita Neog, Cory P. Johnson, Niko Lachmann, Hermann Haller, Yulia Kiyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2024-05-01
Schriftenreihe:Stem Cell Research & Therapy
Schlagworte:
iPSCs
Kidney organoids
Apoptosis
Monocytes
iPSCs-macrophages
Autophagy
Online-Zugang:https://doi.org/10.1186/s13287-024-03739-8
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