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Monocytes prevent apoptosis of iPSCs and promote differentiation of kidney organoids

Abstract Background Induced pluripotent stem cells (iPSCs)-derived kidney organoids are a promising model for studying disease mechanisms and renal development. Despite several protocols having been developed, further improvements are needed to overcome existing limitations and enable a wider applic...

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Glavni autori: Ekaterina Pecksen, Sergey Tkachuk, Cristoph Schröder, Marc Vives Enrich, Anindita Neog, Cory P. Johnson, Niko Lachmann, Hermann Haller, Yulia Kiyan
Format: Artigo
Jezik:Inglês
Izdano: BMC 2024-05-01
Serija:Stem Cell Research & Therapy
Teme:
iPSCs
Kidney organoids
Apoptosis
Monocytes
iPSCs-macrophages
Autophagy
Online pristup:https://doi.org/10.1186/s13287-024-03739-8
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