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Is Nef the elusive cause of HIV-associated hematopoietic dysfunction?

HIV-associated hematological abnormalities involve all lineages of blood cells, thus implying that the virus impairs the function of early HSCs. However, the underlying mechanisms of this defect are unknown, particularly since HSCs are largely resistant to HIV-1 infection. In this issue of the JCI,...

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Autors principals: Kirchhoff, Frank, Silvestri, Guido
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323195/
https://ncbi.nlm.nih.gov/pubmed/18431512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35487
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