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Viremic long-term nonprogressive HIV-1 infection is not associated with abnormalities in known Nef functions

BACKGROUND: A small minority of HIV-1-infected individuals show low levels of immune activation and do not develop immunodeficiency despite high viral loads. Since the accessory viral Nef protein modulates T cell activation and plays a key role in the pathogenesis of AIDS, we investigated whether sp...

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Detalhes bibliográficos
Main Authors: Heigele, Anke, Camerini, David, van’t Wout, Angélique B, Kirchhoff, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3927655/
https://ncbi.nlm.nih.gov/pubmed/24495362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-13
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