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Is Nef the elusive cause of HIV-associated hematopoietic dysfunction?

HIV-associated hematological abnormalities involve all lineages of blood cells, thus implying that the virus impairs the function of early HSCs. However, the underlying mechanisms of this defect are unknown, particularly since HSCs are largely resistant to HIV-1 infection. In this issue of the JCI,...

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Detalhes bibliográficos
Main Authors: Kirchhoff, Frank, Silvestri, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323195/
https://ncbi.nlm.nih.gov/pubmed/18431512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35487
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