STAT3 and STAT1 mediate IL-11–dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice

Deregulated activation of STAT3 is frequently associated with many human hematological and epithelial malignancies, including gastric cancer. While exaggerated STAT3 signaling facilitates an antiapoptotic, proangiogenic, and proproliferative environment for neoplastic cells, the molecular mechanisms...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ernst, Matthias, Najdovska, Meri, Grail, Dianne, Lundgren-May, Therese, Buchert, Michael, Tye, Hazel, Matthews, Vance B., Armes, Jane, Bhathal, Prithi S., Hughes, Norman R., Marcusson, Eric G., Karras, James G., Na, Songqing, Sedgwick, Jonathon D., Hertzog, Paul J., Jenkins, Brendan J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2008
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323192/
https://ncbi.nlm.nih.gov/pubmed/18431520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34944
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg