STAT3 and STAT1 mediate IL-11–dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice

Deregulated activation of STAT3 is frequently associated with many human hematological and epithelial malignancies, including gastric cancer. While exaggerated STAT3 signaling facilitates an antiapoptotic, proangiogenic, and proproliferative environment for neoplastic cells, the molecular mechanisms...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ernst, Matthias, Najdovska, Meri, Grail, Dianne, Lundgren-May, Therese, Buchert, Michael, Tye, Hazel, Matthews, Vance B., Armes, Jane, Bhathal, Prithi S., Hughes, Norman R., Marcusson, Eric G., Karras, James G., Na, Songqing, Sedgwick, Jonathon D., Hertzog, Paul J., Jenkins, Brendan J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323192/
https://ncbi.nlm.nih.gov/pubmed/18431520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34944
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados