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A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity.

The variable portions of antigen receptor genes are assembled from component gene segments by a site-specific recombination reaction known as V(D)J recombination. The RAG1 and RAG2 proteins are the critical lymphoid cell-specific components of the recombination enzymatic machinery and are responsibl...

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Bibliografiska uppgifter
Huvudupphovsmän: McMahan, C J, Difilippantonio, M J, Rao, N, Spanopoulou, E, Schatz, D G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC232308/
https://ncbi.nlm.nih.gov/pubmed/9234712
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