Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells.

The effects of transforming growth factor beta (TGF-beta) were studied in closely related human mammary epithelial cells (HMEC), both finite-life-span 184 cells and immortal derivatives, 184A1S, and 184A1L5R, which differ in their cell cycle responses to TGF-beta but express type I and type II TGF-b...

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Dettagli Bibliografici
Autori principali: Sandhu, C, Garbe, J, Bhattacharya, N, Daksis, J, Pan, C H, Yaswen, P, Koh, J, Slingerland, J M, Stampfer, M R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC232094/
https://ncbi.nlm.nih.gov/pubmed/9111314
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