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Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6.

Cyclin D-dependent kinases act as mitogen-responsive, rate-limiting controllers of G1 phase progression in mammalian cells. Two novel members of the mouse INK4 gene family, p19 and p18, that specifically inhibit the kinase activities of CDK4 and CDK6, but do not affect those of cyclin E-CDK2, cyclin...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Hirai, H, Roussel, M F, Kato, J Y, Ashmun, R A, Sherr, C J
פורמט: Artigo
שפה:Inglês
יצא לאור: 1995
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC230497/
https://ncbi.nlm.nih.gov/pubmed/7739547
תגים: הוספת תג
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