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Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6.

Cyclin D-dependent kinases act as mitogen-responsive, rate-limiting controllers of G1 phase progression in mammalian cells. Two novel members of the mouse INK4 gene family, p19 and p18, that specifically inhibit the kinase activities of CDK4 and CDK6, but do not affect those of cyclin E-CDK2, cyclin...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hirai, H, Roussel, M F, Kato, J Y, Ashmun, R A, Sherr, C J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1995
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC230497/
https://ncbi.nlm.nih.gov/pubmed/7739547
Tagiau: Ychwanegu Tag
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