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Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1.

Heparin-binding epidermal growth factor (HB-EGF) gene transcription is rapidly activated in NIH 3T3 cells transformed by oncogenic Ras and Raf and mediates the autocrine activation of the c-Jun N-terminal kinases (JNKs) observed in these cells. A 1.7-kb fragment of the promoter of the murine HB-EGF...

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Publicado no:Mol Cell Biol
Principais autores: McCarthy, S A, Chen, D, Yang, B S, Garcia Ramirez, J J, Cherwinski, H, Chen, X R, Klagsbrun, M, Hauser, C A, Ostrowski, M C, McMahon, M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232089/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9111309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.5.2401
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