Activated Raf-1 causes growth arrest in human small cell lung cancer cells.

Small cell lung cancer (SCLC) accounts for 25% of all lung cancers, and is almost uniformly fatal. Unlike other lung cancers, ras mutations have not been reported in SCLC, suggesting that activation of ras-associated signal transduction pathways such as the raf-MEK mitogen-activated protein kinases...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Ravi, R K, Weber, E, McMahon, M, Williams, J R, Baylin, S, Mal, A, Harter, M L, Dillehay, L E, Claudio, P P, Giordano, A, Nelkin, B D, Mabry, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508551/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9421477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI831
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