Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase.

The K562 erythroleukemia cell line was used to study the molecular mechanisms regulating lineage commitment of hematopoietic stem cells. Phorbol esters, which initiate megakaryocyte differentiation in this cell line, caused a rapid increase in extracellular-signal-regulated kinase (ERK), which remai...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Whalen, A M, Galasinski, S C, Shapiro, P S, Nahreini, T S, Ahn, N G
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1997
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121442/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.1947
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