Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase.

The K562 erythroleukemia cell line was used to study the molecular mechanisms regulating lineage commitment of hematopoietic stem cells. Phorbol esters, which initiate megakaryocyte differentiation in this cell line, caused a rapid increase in extracellular-signal-regulated kinase (ERK), which remai...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Whalen, A M, Galasinski, S C, Shapiro, P S, Nahreini, T S, Ahn, N G
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121442/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.1947
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