Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase.

The K562 erythroleukemia cell line was used to study the molecular mechanisms regulating lineage commitment of hematopoietic stem cells. Phorbol esters, which initiate megakaryocyte differentiation in this cell line, caused a rapid increase in extracellular-signal-regulated kinase (ERK), which remai...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Mol Cell Biol
Prif Awduron:	Whalen, A M, Galasinski, S C, Shapiro, P S, Nahreini, T S, Ahn, N G
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Taylor & Francis 1997
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9121442/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.4.1947
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