The transcription factor E2F-1 is a downstream target of RB action.
Reintroduction of RB into SAOS2 (RB-/-) cells causes a G1 arrest and characteristic cellular swelling. Coexpression of the cellular transcription factor E2F-1 could overcome these effects. The ability of E2F-1 to bind to RB was neither necessary nor sufficient for this effect, and S-phase entry was...
Tallennettuna:
| Julkaisussa: | Mol Cell Biol |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
1995
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231942/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823942/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.742 |
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