The transcription factor E2F-1 is a downstream target of RB action.

Reintroduction of RB into SAOS2 (RB-/-) cells causes a G1 arrest and characteristic cellular swelling. Coexpression of the cellular transcription factor E2F-1 could overcome these effects. The ability of E2F-1 to bind to RB was neither necessary nor sufficient for this effect, and S-phase entry was...

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Bibliografske podrobnosti

izdano v:	Mol Cell Biol
Principais autores:	Qin, X Q, Livingston, D M, Ewen, M, Sellers, W R, Arany, Z, Kaelin, W G
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 1995
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231942/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7823942/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.2.742
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